| Cat.No.: | PE-1219 |
| Product Name: | Recombinant Human ARID4A protein, GST-tagged |
| Product Overview: | Human ARID4A partial ORF ( NP_002883, 1033 a.a. - 1139 a.a.) recombinant protein with GST-tag at N-terminal. |
| Description: | The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described. [provided by RefSeq, Jul 2008] |
| Applications: | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 37.51 kDa |
| Species: | Human |
| Tag: | GST |
| Amino Acid Sequence: | AEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSSKCTPVKHLNVSKPQKLAR |
| Expression System: | Wheat Germ |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | ARID4A AT rich interactive domain 4A (RBP1-like) [ Homo sapiens ] |
| Gene ID NCBI: | 5926 |
| Official Symbol: | ARID4A |
| Synonyms: | ARID4A; AT rich interactive domain 4A (RBP1-like); RBBP1, retinoblastoma binding protein 1; AT-rich interactive domain-containing protein 4A; RBP 1; RBP1; retinoblastoma binding protein 1; retinoblastoma-binding protein 1; ARID domain-containing protein 4A; RBBP1; RBP-1; RBBP-1; |
| mRNA Refseq: | NM_002892 |
| Protein Refseq: | NP_002883 |
| MIM: | 180201 |
| UniProt ID: | P29374 |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0001 | Human ARHGEF1 Knockout Cell Line 8bp deletion | Inquiry |
| CL-0002 | Human ARHGEF15 Knockout Cell Line | Inquiry |
| CL-0003 | Human ARHGEF11 Knockout Cell Line | Inquiry |
| CL-0004 | Human ARHGEF10L Knockout Cell Line | Inquiry |
| CL-0005 | Human ARHGEF12 Knockout Cell Line | Inquiry |
| Related Gene / Proteins | |||
| ARD1A | ARF1 | ARHGEF1 | ARHGEF10 |
| ARHGEF10L | ARHGEF11 | ARHGEF12 | ARHGEF15 |
| ARHGEF16 | ARHGEF17 | ARHGEF18 | ARHGEF19 |
| ARID1A | ARID1B | ARID2 | ARID3A |
| ARID4A | ARID5A | ARID5B | ARIH2 More > |
| AROS | ARTD10 | ||
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