| Cat.No.: | PE-1263 |
| Product Name: | Recombinant Human TEC (Active), GST-tagged |
| Product Overview: | Full-length recombinant human TEC was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
| Description: | TEC is a member of the Tec family of non-receptor protein-tyrosine kinases that are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. TEC is an integral component of T cell signaling and has a distinct role in T cell activation. Defects in TEC may be associated with myelodysplastic syndrome. TEC plays a crucial role in regulating FGF2 secretion under various physiological conditions and it inhibits CD25 expression in human T-lymphocyte. |
| Applications: | Kinase Assay, Western Blot |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | ~103 kDa |
| Purity: | >75% |
| Species: | Human |
| Formulation: | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Tag: | GST |
| Activity: | 10 nmol/min/mg |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | Full length |
| Concentrations: | 0.1μg/μl |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | NR4A3 nuclear receptor subfamily 4, group A, member 3 [ Homo sapiens ] |
| Gene ID NCBI: | 8013 |
| Synonyms: | NR4A3; nuclear receptor subfamily 4, group A, member 3; nuclear receptor subfamily 4 group A member 3; CHN; CSMF; MINOR; NOR1; nuclear hormone receptor NOR-1; neuron-derived orphan receptor 1; mitogen-induced nuclear orphan receptor; translocated in extraskeletal chondrosarcoma; chondrosarcoma, extraskeletal myxoid, fused to EWS; TEC; |
| mRNA Refseq: | NM_006981 |
| Protein Refseq: | NP_008912 |
| MIM: | 600542 |
| UniProt ID: | Q92570 |
| Chromosome Location: | 9q22 |
| Function: | DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; binding; metal ion binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; thyroid hormone receptor activity; zinc ion binding; |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0076 | Recombinant Human NR2E1 Cell Lysate | Inquiry |
| EL-0130 | Recombinant Human NRIP1 293 Cell Lysate | Inquiry |
| EL-0166 | Recombinant Human NR4A3 293 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0400 | Iberin | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0626 | Recombinant Chicken NR2E1 | Inquiry |
| Related Gene / Proteins | |||
| NR0B1 | NR2C2 | NR2E1 | NR2F2 |
| NR3C1 | NR4A3 | NRF1 | Nrf2 |
| NRIP1 | NRMT1 | NRU | |
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