| Cat.No.: | PE-1361 |
| Product Name: | Recombinant Human HIST1H2AG Protein, HIS-tagged |
| Product Overview: | Recombinant Human HIST1H2AG fused with His tag at N-terminal was expressed in E. coli. |
| Description: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 14.1 kDa |
| Purity: | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Species: | Human |
| Formulation: | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
| Tag: | HIS |
| Expression System: | E. coli |
| Concentrations: | >50 ug/mL as determined by microplate BCA method |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | HIST1H2AG histone cluster 1 H2A family member g [ Homo sapiens (human) ] |
| Gene ID NCBI: | 8969 |
| Official Symbol: | HIST1H2AG |
| Synonyms: | H2AG; H2A/p; H2AFP; H2A.1b; pH2A/f; HIST1H2AG; |
| mRNA Refseq: | NM_021064 |
| Protein Refseq: | NP_066408 |
| MIM: | 615012 |
| UniProt ID: | P0C0S8 |
| Product Types | ||
| ◆ Nucleosomes | ||
| NUC-0007 | Recombinant Tetranucleosomes H3.3 | Inquiry |
| NUC-0008 | Recombinant Mononucleosomes H3.3 | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0009 | Histone H4 peptide (1-21), Biotin-labeled | Inquiry |
| SP-0010 | Histone H4 peptide (1-21) | Inquiry |
| SP-0012 | Histone H3 peptide (21-44), Biotin-labeled | Inquiry |
| Related Gene / Proteins | |||
| HIC1 | HIF1A | HIF1AN | HINFP |
| HIPK1 | HIPK2 | HIRA | Histone |
| Histone H1 | Histone H2A | Histone H2B | Histone H3 |
| Histone H4 | HIV-1 reverse transcriptase | ||
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