| Cat.No.: | PE-1627 |
| Product Name: | MLL3/WDR5/Ash2L/RbBP5/DPY30 Complex |
| Product Overview: | MLL3/WARD complex of human MLL3 (GenBank Accession No. NM_170606) a.a. 4689-4911(end) with N-terminal His-tag and MW= 27 kDa, human WDR5 (GenBank Accession No. NM_017588), a.a. 2-334(end ) with N-terminal His-tag and MW= 37 kDa, human Ash2L (GenBank Accession No. NM_001105214), a.a. 2-534(end) with N-terminal His-tag and MW= 61 kDa, human RbBP5 (GenBank Accession No. NM_005057), a.a. 2-538(end) with N-terminal His-tag and MW= 60 kDa, and human DPY30 (GenBank Accession No. NM_032574) a.a. 2-99(end) with N-terminal His-tag and MW=12 kDa individually expressed in an E. coli expression system. |
| Applications: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 183 kDa (complex) |
| Species: | Human |
| Formulation: | 40 mM Tris-HCl pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 20% glycerol, 200 mM imidazole, 1 μM ZnCl2, 1mM TCEP. |
| Tag: | His |
| Expression System: | E. coli |
| Protein Length: | MLL3 4689–endother components 2–end |
| Format: | Aqueous buffer solution |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene ID NCBI: | NM_170606 (MLL3), NM_017588 (WDR5), NM_001105214 (Ash2L), NM_005057 (RbBP5), NM_032574 (DPY30) |
| Synonyms: | KMT2C, HALR, MLL3, lysine methyltransferase 2C, KLEFS2 |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0005 | WDR5 Polyclonal Antibody | Inquiry |
| EAb-0043 | RBBP4 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0018 | Human ASH1L Knockout Cell Line 53bp deletion | Inquiry |
| CL-0019 | Human ASXL2 Knockout Cell Line 1bp insertion | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0047 | Recombinant Human RBBP4 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| ASB10 | ASB11 | ASB13 | ASB6 |
| ASB7 | ASB8 | ASB9 | ASF1 |
| ASH1L | ASH2 | ASXL2 | DP1 |
| DP2 | DPEP1 | DPEP3 | DPF3 |
| DPY30 | MLH1 | MLL | mll1 More > |
| MLL2 | MLL3 | MLL4 | MLL5 |
| MLLT1 | MLLT3 | RB1 | RbAp46 |
| RbAp48 | RBB4L | RBBP2 | RBBP4 |
| RBBP5 | RBBP7 | RBBP9 | RBM11 |
| RBM18 | RBM26 | RBM3 | RBM34 |
| RBM38 | RBM39 | RBM41 | RBM42 |
| RBM46 | RBM5 | RBM7 | RBMS1 |
| RBMS2 | RBMS3 | RBMY1A1 | RBMY1F |
| RBPJ | RBPMS | WDHD1 | WDR4 |
| WDR5 | WDR77 | WDR82 | WDTC1 |
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