DNMT3B/DNMT3L Complex, His-tag, GST-tag


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Cat.No.:  PE-1668
Product Name:  DNMT3B/DNMT3L Complex, His-tag, GST-tag
Product Overview:  Complex of human DNA methyl-transferase 3B (DNMT3B), GenBank Accession No. NM_006892, a.a. 564-853(end) with N-terminal His-tag, MW=34 kDa, and DNMT3L (GenBank Accession No. NM_013369), a.a. 160-387(end), with an N-terminal GST-tag, MW = 52 kDa, co-expressed in a baculovirus-infected Sf9 cell expression system.
Applications:  Useful for the study of DNA methylation, screening inhibitors, and selectivity profiling.
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Molecular Weight:  86 kDa (complex)
Species:  Human
Formulation:  40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, and 20% glycerol
Tag:  His, GST
Activity:  ≥0.52 pmol/min/µg.
Expression System:  Sf9 Insect Cells
Protein Length:  564–853(end), DNMT3b; 160–387(end), DNMT3L
Format:  Aqueous buffer solution
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene ID NCBI:  NM_006892(DNMT3B), NM_013369 (DNMT3L)
UniProt ID:  Q9UBC3 (DNMT3B), Q9UJW3 (DNMT3L)

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