| Cat.No.: | PE-1882 |
| Product Name: | PAD3 (human recombinant) |
| Description: | Protein Arginine Deiminases (PADs) are guanidino-modifying enzymes belonging to the amidinotransferase superfamily and are designated PAD1-4 and PAD6. PADs are calcium-dependent enzymes that catalyze the post-translational modification of target proteins by converting arginine to citrulline. The various PADs exhibit tissue specific expression and different subcellular localization. PAD3 is a homodimer that is expressed in the epidermis, hair follicles, and keratinocytes. Substrates of PAD3 include filaggrin, trichohyalin, apoptosis-inducing factor (AIF), vimentin, and other proteins. Both PAD1 and PAD3 are speculated to maintain skin hydration. PAD3 has also been showed to be involved in hair growth and cytoskeletal organization. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 76.4 kDa |
| Purity: | ≥85% (by SDS-PAGE) |
| Species: | human |
| Formulation: | 50 mM HEPES, pH 8.0, containing 300 mM sodium chloride, 1 mM DTT, and 10% glycerol |
| Accession#: | Q9ULW8 |
| Alternative Names: | PADI3;PDI3;Peptidylarginine Deiminase 3;Protein Arginine Deiminase 3 |
| Tag: | His |
| Expression System: | E. coli |
| Protein Length: | 2-664 (full length) |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0059 | PARP Monoclonal Antibody | Inquiry |
| EAb-0061 | PARP Polyclonal Antibody | Inquiry |
| EAb-0062 | PARP (Cleaved) Polyclonal Antibody | Inquiry |
| EAb-0063 | PARP (Cleaved) Polyclonal Antibody | Inquiry |
| EAb-0064 | Paf1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| PABPC1L2A | PABPC5 | PABPN1 | PAD |
| PAD1 | PAD2 | PAD3 | PAD4 |
| PADI1 | PADI2 | PADI3 | PADI4 |
| PADI6 | PAF1 | PAN2 | PAPD1 |
| PAPD4 | PAPD5 | PAPD7 | PAPOLA More > |
| PAPOLB | PARD6A | PARG | PARK2 |
| PARK7 | PARP | PARP1 | PARP10 |
| PARP11 | PARP12 | PARP14 | PARP15 |
| PARP16 | PARP2 | PARP3 | PARP4 |
| PARP6 | PARP7 | PARP8 | PARP9 |
| PAX5 | PAX6 | PAX7 | PAX9 |
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