Paf1 Polyclonal Antibody


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Cat.No.:  EAb-0064
Product Name:  Paf1 Polyclonal Antibody
Product Overview:  Polyclonal Antibody to detect Paf1 in human samples.
Antibody Type:  Polyclonal
Immunogen:  Polyclonal antibody raised in rabbit against human Paf1 (Paf1, RNA polymerase II associated factor, homolog), using the full length recombinant protein.
Host:  Rabbit
Isotype:  IgG
Antibody Target:  Paf1
Purification:  Protein G purified
Appearance:  Colorless liquid
Formulation:  In PBS with 0.05% sodium azide and 0.05% ProClin 300.
Applications:  Western blot, ChIP.
Recommended Dilutions/Conditions:  WB: 1:1000, ChIP: 1-5 µg/ChIP.
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  Western blot: HeLa cells, ChIP.
Species Reactivity:  Human
Shipping:  Gel Pack
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  PD2
Scientific Background:  PAF is a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9, which was first purified from yeast. The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription. The human PAF (hPAF) complex shares four subunits with yPAF (hCtr9, hPaf1, hLeo1 and Cdc73), but contains an additional higher eukaryotic-specific subunit, hSki8. In addition to coordinating events during transcription (initiation, promoter clearance and elongation); PAF also coordinates events in RNA quality control.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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