| Cat.No.: | PE-2046 |
| Product Name: | KDM1A protein-GST fusion |
| Background: | KDM1A or lysine (K)-specific demethylase 1A is a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain that is a component of several histone deacetylase complexes and act as a histone demethylase. H3K4 histone demethylase activity of KDM1A is partly responsible for the repressive activity of TAL1 and restricts TAL1 function in hematopoiesis. KDM1A plays an essential role for CoREST in demethylation of H3K4 both in vitro and in vivo. |
| Applications: | KDM1A Protein is suitable for use in Western Blot. Expect a band approximately ~100kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid (sterile filtered) |
| Purity: | >95% by densitometry |
| Species: | Human |
| Formulation: | 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol |
| Accession#: | BC048134 |
| Alternative Names: | AOF2, BHC110, LSD1, KIAA0601, Lysine-specific histone demethylase 1A,, BRAF35-HDAC complex protein BHC110, Flavin-containing amine oxidase domain-containing protein 2 |
| Tag: | GST |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | 172-end |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0015 | Human KDM5B Knockout Cell Line 14bp deletion | Inquiry |
| CL-0087 | Human KDM1A Knockout Cell Line 10bp deletion | Inquiry |
| CL-0088 | Human KDM1B Knockout Cell Line 13bp deletion | Inquiry |
| CL-0089 | Human KDM2B Knockout Cell Line 14bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0071 | KDM1B Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| KDM1 | KDM1A | KDM1B | KDM2 |
| KDM2A | KDM2B | KDM3A | KDM3B |
| KDM4 | KDM4A | KDM4B | KDM4C |
| KDM4D | KDM4E | KDM5 | KDM5A |
| KDM5B | KDM5C | KDM5D | KDM6A More > |
| KDM6B | KDM6C | KDM7 | KDM7A |
| KDM7B | KDM8 | ||
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