Cat.No.: | PE-2288 |
Product Name: | Recombinant Human NOC2L protein |
Background: | Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter. |
Applications: | ELISA; Western blot |
Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
Appearance: | Liquid |
Species: | Human |
Formulation: | pH: 8.00; Constituents: 0.31% Glutathione, 0.79% Tris HCl |
Alternative Names: | NET15/NET7/NIR |
Tag: | GST |
Amino Acid Sequence: | MAAAGSRKRRLAELTVDEFLASGFDSESESESENSPQAETREAREAARSP DKPGGSPSASRRKGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDS DSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRGLKGKKNSVPVT VAMVERWKQAAKQRLTPKLFHEVVQAFRAAVATTRGDQESAEANKFQVTD SAAFNALVTFCIRDLIGCLQKLLFGKVAKDSSRMLQPSSSPLWGKLRVDI KAYLGSAIQLVSCLSETTVLAAVLRHISVLVPCFLTFPKQCRMLLKRMVV VWSTGEESLRVLAFLVLSRVCRHKKDTFLGPVLKQMYITYVRNCKFTSPG ALPFISFMQWTLTELLALEPGVAYQHAFLYIRQLAIHLRNAMTTRKKETY QSVYNWQYVHCLFLWCRVLSTAGPSEALQPLVYPLAQVIIGCIKLIPTAR FYPLRMHCIRALTLLSGSSGAFIPVLPFILEMFQQVDFNRKPGRMSSKPI NFSVILKLSNVNLQEKAYRDGLVEQLYDLTLEYLHSQAHCIGFPELVLPV VLQLKSFLRECKVANYCRQVQQLLGKVQENSAYICSRRQRVSFGVSEQQA VEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKERLEDLNFPEIKR RKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDE EDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD |
Sequence Similarities: | Belongs to the NOC2 family. |
Expression System: | Wheat germ |
Protein Length: | Full length protein; 1 to 749 |
Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Product Types | ||
◆ Antibodies | ||
EAb-1892 | Notch3 Monoclonal Antibody | Inquiry |
EAb-1893 | Notch1 Monoclonal Antibody | Inquiry |
EAb-1894 | NonO Polyclonal Antibody | Inquiry |
◆ Proteins & Enzymes | ||
PE-2288 | Recombinant Human NOC2L protein | Inquiry |
PE-2349 | Recombinant Human C14orf169 / NO66 protein | Inquiry |
Related Gene / Proteins | |||
NO66 | NOB1 | NOC2L | NonO |
NOP58 | Notch1 | Notch3 |
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