Recombinant Human FTSJD2 protein


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Cat.No.:  PE-2522
Product Name:  Recombinant Human FTSJD2 protein
Background:  S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.
Applications:  Western blot; ELISA
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid
Species:  Human
Formulation:  pH: 8.00; Constituents: 0.31% Glutathione, 0.79% Tris HCl
Alternative Names:  Cap methyltransferase 1/Cap-specific mRNA (nucleoside-2''-O-)-methyltransferase 1/Cap1 2''O-ribose methyltransferase 1
Tag:  GST
Amino Acid Sequence:  MKRRTDPECTAPIKKQKKRVAELALSLSSTSDDEPPSSVSHGAKASTTSL SGSDSETEGKQHSSDSFDDAFKADSLVEGTSSRYSMYNSVSQKLMAKMGF REGEGLGKYSQGRKDIVEASSQKGRRGLGLTLRGFDQELNVDWRDEPEPS ACEQVSWFPECTTEIPDTQEMSDWMVVGKRKMIIEDETEFCGEELLHSVL QCKSVFDVLDGEEMRRARTRANPYEMIRGVFFLNRAAMKMANMDFVFDRM FTNPRDSYGKPLVKDREAELLYFADVCAGPGGFSEYVLWRKKWHAKGFGM TLKGPNDFKLEDFYSASSELFEPYYGEGGIDGDGDITRPENISAFRNFVL DNTDRKGVHFLMADGGFSVEGQENLQEILSKQLLLCQFLMALSIVRTGGH FICKTFDLFTPFSVGLVYLLYCCFERVCLFKPITSRPANSERYVVCKGLK VGIDDVRDYLFAVNIKLNQLRNTDSDVNLVVPLEVIKGDHEFTDYMIRSN ESHCSLQIKALAKIHAFVQDTTLSEPRQAEIRKECLRLWGIPDQARVAPS SSDPKSKFFELIQGTEIDIFSYKPTLLTSKTLEKIRPVFDYRCMVSGSEQ KFLIGLGKSQIYTWDGRQSDRWIKLDLKTELPRDTLLSVEIVHELKGEGK AQRKISAIHILDVLVLNGTDVREQHFNQRIQLAEKFVKAVSKPSRPDMNP IRVKEVYRLEEMEKIFVRLEMKIIKGSSGTPKLSYTGRDDRHFVPMGLYI VRTVNEPWTMGFSKSFKKKFFYNKKTKDSTFDLPADSIAPFHICYYGRLF WEWGDGIRVHDSQKPQDQDKLSKEDVLSFIQMHRA
Sequence Similarities:  Contains 1 G-patch domain.Contains 1 RrmJ-type SAM-dependent 2'-O-MTase domain.Contains 1 WW domain.
Expression System:  Wheat germ
Protein Length:  Full length protein; 1 to 835
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.
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Related Gene / Proteins
FTO FTSJ2 FTSJ3 FTSJD2

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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