Recombinant Mouse PARP2 protein


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Cat.No.:  PE-2660
Product Name:  Recombinant Mouse PARP2 protein
Background:  Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Applications:  SDS-PAGE
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Appearance:  Liquid
Molecular Weight:  63 kDa
Purity:  >98 % SDS-PAGE.
Species:  Mouse
Formulation:  pH: 7.50; Preservative: 0.34% Imidazole; Constituents: 0.2% Tergitol-NP40, 0.79% Tris HCl, 10% Glycerol, 0.58% Sodium chloride
Accession#:  O88554
Alternative Names:  ADP ribosyltransferase like 2/ADP-ribosyltransferase diphtheria toxin-like 2/ADPRT 2
Amino Acid Sequence:  MAPRRQRSGSGRRVLNEAKKVDNGNKATEDDSPPGKKMRTCQRKGPMAGG KDADRTKDNRDSVKTLLLKGKAPVDPECAAKLGKAHVYCEGDDVYDVMLN QTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKTGQHSLVTCSGDLN KAKEIFQKKFLDKTKNNWEDRENFEKVPGKYDMLQMDYAASTQDESKTKE EETLKPESQLDLRVQELLKLICNVQTMEEMMIEMKYDTKRAPLGKLTVAQ IKAGYQSLKKIEDCIRAGQHGRALVEACNEFYTRIPHDFGLSIPPVIRTE KELSDKVKLLEALGDIEIALKLVKSERQGLEHPLDQHYRNLHCALRPLDH ESNEFKVISQYLQSTHAPTHKDYTMTLLDVFEVEKEGEKEAFREDLPNRM LLWHGSRLSNWVGILSHGLRVAPPEAPITGYMFGKGIYFADMSSKSANYC FASRLKNTGLLLLSEVALGQCNELLEANPKAQGLLRGKHSTKGMGKMAPS PAHFITLNGSTVPLGPASDTGILNPEGYTLNYNEFIVYSPNQVRMRYLLK IQFNFLQLW
Sequence Similarities:  Contains 1 PARP alpha-helical domain.Contains 1 PARP catalytic domain.
Expression System:  Sf21 Insect Cells
Post Translational Modifications:  Poly-ADP-ribosylated by PARP1.
Protein Length:  Full length protein; 1 to 559
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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