| Cat.No.: | PE-2742 |
| Product Name: | Recombinant Human XRCC3 protein (denatured) |
| Background: | Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C. |
| Applications: | SDS-PAGE |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 40 kDa including tags |
| Purity: | > 85 % SDS-PAGE. |
| Species: | Human |
| Formulation: | pH: 8.00; Constituents: 2.4% Urea, 0.32% Tris HCl, 10% Glycerol |
| Accession#: | O43542 |
| Alternative Names: | CMM6/DNA repair protein XRCC3/RAD51 like |
| Tag: | His |
| Amino Acid Sequence: | MGSSHHHHHHSSGLVPRGSHMDLDLLDLNPRIIAAIKKAKLKSVKEVLHF SGPDLKRLTNLSSPEVWHLLRTASLHLRGSSILTALQLHQQKERFPTQHQ RLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQH GGLEAGAVYICTEDAFPHKRLQQLMAQQPRLRTDVPGELLQKLRFGSQIF IEHVADVDTLLECVNKKVPVLLSRGMARLVVIDSVAAPFRCEFDSQASAP RARHLQSLGATLRELSSAFQSPVLCINQVTEAMEEQGAAHGPLGFWDERV SPALGITWANQLLVRLLADRLREEEAALGCPARTLRVLSAPHLPPSSCSY TISAEGVRGTPGTQSH |
| Sequence Similarities: | Belongs to the RecA family. RAD51 subfamily. |
| Expression System: | E. coli |
| Post Translational Modifications: | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| Protein Length: | Full length protein; 1 to 346 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0002 | XRCC3 Polyclonal Antibody | Inquiry |
| EAb-0299 | XRCC3 Polyclonal Antibody | Inquiry |
| EAb-1777 | XRCC1 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0456 | Human XRCC4 Knockout Cell Line 8bp deletion | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-2742 | Recombinant Human XRCC3 protein (denatured) | Inquiry |
| Related Gene / Proteins | |||
| XRCC1 | XRCC3 | XRCC4 | |
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