| Cat.No.: | PE-2868 |
| Product Name: | Recombinant human CCL14 protein |
| Background: | Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca(2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. |
| Applications: | Functional Studies; SDS-PAGE |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Lyophilised |
| Molecular Weight: | 59 kDa |
| Species: | Human |
| Accession#: | Q16627 |
| Alternative Names: | CC-1/CC-3/CCL14 |
| Amino Acid Sequence: | TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN |
| Sequence Similarities: | Belongs to the intercrine beta (chemokine CC) family. |
| Expression System: | E. coli |
| Post Translational Modifications: | The N-terminal processed forms HCC-1(3-74), HCC-1(4-74) and HCC-1(9-74) are produced in small amounts by proteolytic cleavage after secretion in blood.HCC-1(1-74), but not HCC-1(3-74) and HCC-1(4-74), is partially O-glycosylated; the O-linked glycan consists of one Gal-GalNAc disaccharide, further modified by two N-acetylneuraminic acids. |
| Protein Length: | Full length protein |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0060 | Recombinant Human CCND1 293 Cell Lysate | Inquiry |
| EL-0120 | Recombinant Human CCNB1 Cell Lysate | Inquiry |
| EL-0197 | Recombinant Human CCDC101 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0515 | Recombinant Human Cyclin D1, GST-tagged | Inquiry |
| PE-0516 | Recombinant Human CCND1, His-tagged | Inquiry |
| Related Gene / Proteins | |||
| CCDC101 | CCL14 | CCNB1 | CCND1 |
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