| Cat.No.: | PE-3490 |
| Product Name: | Recombinant KDM6C protein |
| Product Overview: | Recombinant KDM6C (accession number NP_009056.3) was expressed in Sf9 cells as full length protein and contains an N-terminal FLAG-Tag with an observed molecular weight of 152.9 kDa. The recombinant protein is >70% pure by SDS-PAGE. |
| Background: | KDM6C (lysine (K)-specific demethylase 6C), also known as UTY (Ubiquitously Transcribed Tetratricopeptide Repeat Containing, Y-Linked) is a KDM6 subfamily member that catalyzes demethylation of N-methylated histone 3 lysine 27 (H3K27), a mark important for transcriptional repression. The activity of UTY (KDM6C) is much weaker than KDM6A and KDM6B, due to point substitutions involved in substrate binding. |
| Applications: | Suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Species: | Human |
| Formulation: | 25 mM HEPES pH 7.5, 300 mM NaCl, 5% glycerol, 0.04% Triton X-100, 0.2 mM TCEP. |
| Tag: | FLAG |
| Expression System: | Baculovirus |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0015 | Human KDM5B Knockout Cell Line 14bp deletion | Inquiry |
| CL-0087 | Human KDM1A Knockout Cell Line 10bp deletion | Inquiry |
| CL-0088 | Human KDM1B Knockout Cell Line 13bp deletion | Inquiry |
| CL-0089 | Human KDM2B Knockout Cell Line 14bp deletion | Inquiry |
| ◆ Antibodies | ||
| EAb-0071 | KDM1B Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| KDM1 | KDM1A | KDM1B | KDM2 |
| KDM2A | KDM2B | KDM3A | KDM3B |
| KDM4 | KDM4A | KDM4B | KDM4C |
| KDM4D | KDM4E | KDM5 | KDM5A |
| KDM5B | KDM5C | KDM5D | KDM6A More > |
| KDM6B | KDM6C | KDM7 | KDM7A |
| KDM7B | KDM8 | ||
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