| Cat.No.: | EKIT-0551 |
| Product Name: | LSD2(KDM1B) Homogeneous Assay Kit (Monomethyl) |
| Size: | 384 reactions |
| Description: | The LSD2(KDM1B) Homogeneous Assay Kit (Monomethyl) is designed to measure the activity of lysine-specific demethylase (LSD2) for screening and profiling applications. LSD2, also called KDM1B, is a chromatin-modifying enzyme that specifically removes methyl groups from mono- and dimethylated Lys of histone H3, thereby acting as a corepressor of transcription. LSD2 is a potential target for drug development. The LSD2 Homogeneous Assay Kit (Monomethyl) comes in a convenient AlphaLISA format, with biotinylated, mono-methylated histone H3 (1MeK4) peptide substrate, primary antibody to detect non-methylated product, LSD2 assay buffer, and purified LSD2 for 384 enzyme reactions. The key to the LSD2 Homogeneous Assay Kit (Monomethyl) is a highly specific antibody that recognizes demethylated substrate. With this kit, only three simple steps on a microtiter plate are required for demethylase detection. First, a sample containing LSD2 enzyme is incubated with the biotinylated substrate. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts. |
| Applications: | For studying enzyme kinetics and HTS applications. |
| Kit Components: | The LSD2 Homogeneous Assay Kit 1 comes in a convenient AlphaLISA format, with biotinylated, mono-methylated histone H3 (1MeK4) peptide substrate, primary antibody to detect non-methylated product, LSD2 assay buffer, and purified LSD2. |
| Warning: | For research use only, not for diagnostic use. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0015 | Human KDM5B Knockout Cell Line 14bp deletion | Inquiry |
| CL-0087 | Human KDM1A Knockout Cell Line 10bp deletion | Inquiry |
| CL-0088 | Human KDM1B Knockout Cell Line 13bp deletion | Inquiry |
| ◆ Research Kits | ||
| EKIT-0062 | Histone Demethylase LSD1 Activity/Inhibition Assay Kit | Inquiry |
| ◆ Antibodies | ||
| EAb-0071 | KDM1B Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| KDM1 | KDM1A | KDM1B | KDM2 |
| KDM2A | KDM2B | KDM3A | KDM3B |
| KDM4 | KDM4A | KDM4B | KDM4C |
| KDM4D | KDM4E | KDM5 | KDM5A |
| KDM5B | KDM5C | KDM5D | KDM6A More > |
| KDM6B | KDM6C | KDM7 | KDM7A |
| KDM7B | KDM8 | LSD1 | LSD2 |
| LSM2 | LSM3 | LSM5 | LSM6 |
| LSP1 | |||
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