| Cat.No.: | BSM-0116 |
| Product Name: | Droxinostat |
| CAS No.: | 99873-43-5 |
| Figure: |
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| Synonyms: | 4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide |
| Description: | Droxinostat has shown a potent action against HDAC3, HDAC6, and HDAC8 which are pyrimidyl-hydroxamic acid-dependent histone deacetylases. Droxinostat sensitizes cells to apoptosis by decreasing c-FLIPL and c-FLIPS expression, reducing cell survival, and inducing apoptosis. |
| Appearance: | Crystalline solid |
| Molecular Weight: | 243.69 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | HDAC3, HDAC6, and HDAC8 |
| Molecular Formula: | C11H14ClNO3 |
| MDL Number: | MFCD01326592 |
| Solubility: | DMSO (>40 mg/ml) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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