| Cat.No.: | BSM-0175 |
| Product Name: | MS-275 (Entinostat, SNDX-275) |
| CAS No.: | 209783-80-2 |
| Figure: |
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| Synonyms: | Entinostat, Pyridin-3-ylmethyl 4-((2-aminophenyl)carbamoyl)benzylcarbamate |
| Description: | An inhibitor of histone deacetylases (HDACs) and preferentially inhibits HDAC1 over HDAC3. Has no inhibitory activity towards HDAC8 (IC50>100 µM).Suppresses the p38 MAP kinase pathway in rheumatoid arthritic synovial fibroblasts. Active in vivo. |
| Appearance: | Crystalline solid |
| Molecular Weight: | 376.41 |
| Purity: | ≥99% by HPLC |
| Storage: | -20°C |
| Targets: | HDAC1 and HDAC3 |
| Molecular Formula: | C21H20N4O3 |
| MDL Number: | MFCD08272435 |
| Solubility: | DMSO (38 mg/ml) |
| Shipping Conditions: | RT |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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