| Cat.No.: | BSM-0190 |
| Product Name: | Panobinostat (LBH589) |
| CAS No.: | 404950-80-7 |
| Figure: |
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| Synonyms: | LBH589; LBN-589; NVP-LBH589; (E)-N-hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide |
| Description: | A highly active, non-selective HDAC inhibitor. Cotreatment with panobinostat and an HSP90 inhibitor caused synergistic apoptosis in human CML-BC and AML cells. A potent antimyeloma agent that overcomes drug resistance. |
| Appearance: | Crystalline solid |
| Molecular Weight: | 349.43 |
| Purity: | ≥99% by HPLC |
| Storage: | -20°C |
| Targets: | HDAC |
| Molecular Formula: | C21H23N3O2 |
| MDL Number: | MFCD09833242 |
| Solubility: | DMSO |
| Shipping Conditions: | RT |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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