| Cat.No.: | BSM-0244 |
| Product Name: | UNC 1215 |
| CAS No.: | 1415800-43-9 |
| Figure: |
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| Synonyms: | (2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone |
| Description: | Cell-permeable. A potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. It binds L3MBTL3 with a Kd value of 120 nM (IC₅₀ = 40 nM), competitively displacing mono- or dimethyl-lysine containing peptides. UNC1215 is > 50-fold selective toward L3MBTL3 than other members of the human MBT family and demonstrates selectivity against more than 200 other Kme reader domains examined. |
| Appearance: | White to Off-white Solid |
| Molecular Weight: | 529.72 |
| Purity: | ≥98% by HPLC |
| Storage: | -20°C |
| Targets: | L3MBTL3 domain |
| Molecular Formula: | C₃₂H₄₃N₅O₂ |
| MDL Number: | MFCD00236452 |
| Solubility: | DMSO (50 mM) |
| Shipping Conditions: | Gel Pack |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0070 | L3MBTL1 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0077 | Recombinant Human L3MBTL1 Cell Lysate | Inquiry |
| ◆ Cell Lines | ||
| CL-0097 | Human L3MBTL2 Knockout Cell Line 8bp deletion | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0244 | UNC 1215 | Inquiry |
| BSM-0245 | UNC-669 | Inquiry |
| Related Gene / Proteins | |||
| L3MBTL1 | L3MBTL2 | L3MBTL3 | L3MBTL4 |
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