| Cat.No.: | BSM-0304 |
| Product Name: | 5-Nitroso-8-quinolinol |
| CAS No.: | 3565-26-2 |
| Figure: |
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| Synonyms: | Hydron III; NSC 3852 |
| Product Overview: | A tumor cell differentiating agent |
| Description: | 5-Nitroso-8-quinolinol is a chemically unique HDAC inhibitor that harbors a different Zn2+ chelation motif compared to SAHA. As an antitumor agent, 10 μM 5-nitroso-8-quinolinol can induce oxidative stress contributing to apoptosis and differentiation in MCF-7 breast cancer cells. Additionally, 5-nitroso-8-quinolinol inhibits T. gondii tachyzoite propagation in human fibroblasts with an EC50 value of 80 nM and inhibits P. falciparum growth in human red blood cells with an EC50 value of 1.3 μM. |
| Appearance: | A crystalline solid |
| Molecular Weight: | 174.2 |
| Purity: | ≥95% |
| Storage: | -20°C |
| Targets: | HDAC |
| Molecular Formula: | C9H6N2O2 |
| Chemical Name: | 5-nitroso-8-quinolinol |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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