| Cat.No.: | BSM-0313 |
| Product Name: | HPOB |
| CAS No.: | 1429651-50-2 |
| Figure: |
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| Product Overview: | A potent and selective inhibitor of HDAC6 |
| Description: | HPOB is a potent inhibitor of histone deacetylase 6 (HDAC6; IC50 = 56 nM). It is at least 30-fold less effective against other HDACs. Through its effects on HDAC6, HPOB induces acetylation of α-tubulin but not histones. HPOB reduces the growth, but not the viability, of normal and transformed cells. It enhances the death of transformed cells as triggered by the topoisomerase II inhibitors etoposide and doxorubicin. |
| Appearance: | A crystalline solid |
| Molecular Weight: | 314.3 |
| Purity: | ≥95% |
| Storage: | -20°C |
| Targets: | HDAC7 |
| Molecular Formula: | C17H18N2O4 |
| Chemical Name: | 4-[(hydroxyamino)carbonyl]-N-(2-hydroxyethyl)-N-phenyl-benzeneacetamide |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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