HDAC3 Inhibitor


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Cat.No.:  BSM-0368
Product Name:  HDAC3 Inhibitor
CAS No.:  2044701-99-5
Figure: 
Synonyms:  Histone Deacetylase 3
Product Overview:  An allosteric HDAC3 inhibitor
Description:  HDAC3 inhibitor is an allosteric inhibitor of histone deacetylase 3 (HDAC3; Ki = 0.16 nM). It is selective for HDAC3 over HDAC1 and HDAC2 (IC50s = 0.95, 11.81, and 95.45 nM, respectively, using recombinant HDACs). In addition, it is selective for acute myeloid, monocytic, and lymphoblastic leukemia cell lines (EC50s = 36.37, 76.64, and 151.7 nM, respectively) over chronic myeloid, acute promyelocytic, and acute lymphoblastic cells (EC50s = 2,160, >10,000, and >10,000 nM, respectively).
Appearance:  A solution in ethanol
Molecular Weight:  337.4
Purity:  ≥98%
Storage:  -20°C
Targets:  HDAC3
Molecular Formula:  C20H23N3O2
Chemical Name:  4-[[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]amino]methyl]-benzoic acid 2-propylhydrazide
Warning:  For Research Use Only! Not For Use in Humans.

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