| Cat.No.: | EL-0218 |
| Product Name: | Recombinant Human MSH6 293 Cell Lysate |
| Description: | Antigen standard for mutS homolog 6 (E. coli) (MSH6) is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection. |
| Species: | Human |
| Source: | HEK 293 Cells |
| Components: | This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol). |
| Storage: | Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. |
| Warning: | For research use only, not for diagnostic or therapeutic use. |
| Gene ID NCBI: | 2956 |
| Official Symbol: | MSH6 |
| Official Full Name: | mutS homolog 6 |
| Synonyms: | MSH6; mutS homolog 6 (E. coli); GTBP, mutS (E. coli) homolog 6; DNA mismatch repair protein Msh6; p160; GTMBP; hMSH6; sperm-associated protein; mutS-alpha 160 kDa subunit; G/T mismatch-binding protein; GTBP; HSAP; HNPCC5; |
| mRNA Refseq: | NM_000179 |
| Protein Refseq: | NP_000170 |
| MIM: | 600678 |
| UniProt ID: | P52701 |
| Chromosome Location: | 2p16 |
| Function: | contributes_to ADP binding; contributes_to ATP binding; contributes_to ATPase activity; DNA-dependent ATPase activity; contributes_to MutLalpha complex binding; chromatin binding; damaged DNA binding; contributes_to double-stranded DNA binding; contributes_to four-way junction DNA binding; contributes_to guanine/thymine mispair binding; contributes_to magnesium ion binding; contributes_to mismatched DNA binding; nucleotide binding; contributes_to oxidized purine DNA binding; protein binding; contributes_to protein binding; NOT protein homodimerization activity; contributes_to single guanine insertion binding; contributes_to single thymine insertion binding; |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0104 | Recombinant Human MSL1 Lysate | Inquiry |
| EL-0193 | Recombinant Human MSL3 293 Cell Lysate | Inquiry |
| EL-0194 | Recombinant Human MSL3 293 Cell Lysate | Inquiry |
| EL-0218 | Recombinant Human MSH6 293 Cell Lysate | Inquiry |
| EL-0227 | Recombinant Human MSL2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| MS4A7 | MSH2 | MSH3 | MSH5 |
| MSH6 | MSI2 | MSL1 | MSL2 |
| MSL3 | MSP58 | MST1 | MSY2 |
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