| Cat.No.: | EAb-0007 |
| Product Name: | USP25 Polyclonal Antibody |
| Product Overview: | Polyclonal antibody to detect USP25 (a DUB enzyme) in human, mouse and rat samples. |
| Antibody Type: | Polyclonal |
| Immunogen: | Fusion protein of human USP25 |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | USP25 |
| Purification: | Affinity purified |
| Appearance: | Colorless liquid |
| Formulation: | 100 µg of antibody in 100 µl PBS containing 0.02% sodium azide, 50% glycerol, pH 7.3 |
| Applications: | Western blot |
| Recommended Dilutions/Conditions: |
Western blot: 1:500 – 1:1000 dilution. Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | Western Blot: BxPC-3 cell lysate |
| Species Reactivity: | Human, mouse, rat |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q9UHP3 |
| Alternative Name: | USP25, USP21 |
| Scientific Background: | Ubiquitinating enzymes (UBEs) catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzymes (DUB) action. There are five DUB subfamilies including the USP, UCH, OTU, MJD, and JAMM enzymes. USP25 (ubiquitin specific peptidase 25), also known as USP21, is a 1087 amino acid member of the peptidase C19 family. Expressed at high amounts in pancreas, kidney, skeletal muscle, testis, liver, heart, brain and lung, USP25 associates with the 26S proteasome and functions as a deubiquitinating enzyme in the Ub proteolytic pathway. Due to alternative splicing events, USP25 is expressed as two short, ubiquitously expressed isoforms and one long, muscle specific isoform. The long isoform of USP25 is upregulated in myogenesis and is implicated in the pathogenesis of severe myopathies. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0006 | USP3 Polyclonal Antibody | Inquiry |
| EAb-0007 | USP25 Polyclonal Antibody | Inquiry |
| EAb-0008 | USP2 Polyclonal Antibody | Inquiry |
| EAb-0009 | USP1 Polyclonal Antibody | Inquiry |
| EAb-0010 | USP7 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| USF1 | USP1 | USP10 | USP11 |
| USP12 | USP13 | USP14 | USP15 |
| USP16 | USP17L11 | USP17L12 | USP17L13 |
| USP17L15 | USP17L17 | USP17L1P | USP17L2 |
| USP17L22 | USP17L28 | USP17L3 | USP17L5 More > |
| USP17L8 | USP18 | USP19 | USP2 |
| USP20 | USP21 | USP22 | USP24 |
| USP25 | USP26 | USP27X | USP28 |
| USP29 | USP3 | USP30 | USP31 |
| USP32 | USP33 | USP34 | USP35 |
| USP36 | USP37 | USP38 | USP40 |
| USP42 | USP43 | USP44 | USP45 |
| USP46 | USP47 | USP48 | USP49 |
| USP5 | USP53 | USP54 | USP6 |
| USP6NL | USP7 | USP8 | USP9X |
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
