| Cat.No.: | EAb-0013 |
| Product Name: | TP2 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide surrounding amino acid 572 of human TP2. |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | TP2 |
| Purification: | Affinity purified |
| Appearance: | Colorless liquid |
| Formulation: | 100 µg (0.5 mg/ml) affinity purified rabbit anti-TP2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal |
| Applications: | Western blot |
| Recommended Dilutions/Conditions: |
Western blot analysis (1-4 µg/ml). Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | 3T3 cell lysate |
| Species Reactivity: | Human, mouse, rat |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | O14746 |
| Alternative Name: | Telomerase reverse transcriptase, HEST2, Telomerase catalytic subunit, Telomerase-associated protein 2, TP2, TEAP |
| Scientific Background: | Telomerase is an RNA-dependant DNA polymerase that catalyzes the addition of telemoric repeat, TTAGGG to chromosome ends. Telomerase is composed of an internal telomerase RNA template (TERC) and the enzyme, telomerase reverse transcriptase (TERT or TP2). Telomerase expression is usually repressed in postnatal somatic cells resulting in shortening of telomeres. Overexpression of telomerase may be implicated with oncogenesis. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0013 | TP2 Polyclonal Antibody | Inquiry |
| EAb-0623 | p53 Monoclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0053 | UNC-2170 | Inquiry |
| BSM-0324 | UNC2170 (maleate) | Inquiry |
| ◆ Cell Lines | ||
| CL-0438 | Human TP53BP1 Knockout Cell Line 40bp deletion | Inquiry |
| Related Gene / Proteins | |||
| TP2 | TP53BP1 | ||
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