| Cat.No.: | EAb-0020 |
| Product Name: | Suz12 Polyclonal Antibody |
| Product Overview: | Polyclonal Antibody to detect Suz12 in human and mouse samples. |
| Antibody Type: | Polyclonal |
| Immunogen: | Polyclonal antibody raised in rabbit against the N-terminus of recombinant human Suz12 protein (Suppressor of Zeste 12 protein homolog). |
| Host: | Rabbit |
| Isotype: | IgG |
| Antibody Target: | Suz12 |
| Purification: | Protein G purified |
| Appearance: | Colorless liquid |
| Formulation: | In PBS with 0.05% sodium azide and 0.05% ProClin 300. |
| Applications: | Western blot, ChIP. |
| Recommended Dilutions/Conditions: |
ChIP: 10 µg/ChIP, Western Blot: 1:1000 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | Western blot: HeLa cells, ChIP: Mouse ES cells. |
| Species Reactivity: | Human, mouse |
| Shipping: | Gel Pack |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q15022 |
| Alternative Name: | CHET9, JJAZ1 |
| Scientific Background: | Suz12 is a Polycomb group (PcG) protein. These proteins form multiprotein complexes, which keep homeotic genes in a transcriptionally repressive state throughout development. PcG proteins are not required to initiate repression, but maintain it during later stages of development. They probably act via the methylation of histones. Suz12 is a component of the PRC2 complex, which is composed of EED, EZH2, SUZ12/JJAZ1, RBBP4 and RBBP7, and methylates ‘Lys-9’ and ‘Lys-27’ of histone H3. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0020 | Suz12 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0100 | Chaetocin | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0103 | Recombinant Human SUZ12 293 Cell Lysate | Inquiry |
| EL-0132 | Recombinant Human SUV39H1 293 Cell Lysate | Inquiry |
| EL-0137 | Recombinant Human SUV420H1 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| SUDS3 | SUMO | SUMO1 | SUMO2 |
| SUMO3 | SUN1 | Surf6 | suv39h1 |
| SUV39H2 | SUV3L1 | SUV420H1 | SUV420H2 |
| SUZ12 | |||
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