S- Adenosylmethionine Polyclonal Antibody


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Cat.No.:  EAb-0039
Product Name:  S- Adenosylmethionine Polyclonal Antibody
Product Overview:  Polyclonal Antibody to detect S-Adenosylmethionine in samples.
Antibody Type:  Polyclonal
Immunogen:  S-Adenosylmethionine Aza-SAM analog conjugated to KLH
Host:  Rabbit
Isotype:  IgG
Antibody Target:  S Adenosylmethionine
Purification:  Affinity chromatography purified
Appearance:  Colorless liquid
Formulation:  10 mM PBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 1% BSA
Applications:  cELISA, FCM, IHC
Recommended Dilutions/Conditions:  ELISA: 1:2500, FCM: 1: 20/40, IHC: 1: 20/40.
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  IHC: lung carcinoma tissue, FCM: HepG2 and L02 cell lines
Species Reactivity:  All
Shipping:  Gel Pack
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  S- Adenosylmethionine
Scientific Background:  S-Adenosylmethionine (SAM) is a naturally occurring compound that is found in almost every tissue and fluid in the body. It is a common co-substrate involved in methyl group transfers. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyl transferase. Transmethylation, transsulfuration, and aminopropylation are the metabolic pathways that use SAM. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver. SAM plays a role in the immune system, maintains cell membranes, and helps produce and break down brain chemicals, such as serotonin, melatonin, and dopamine. It works with vitamin B12 and folate (vitamin B9). Being deficient in either vitamin B12 or folate may reduce levels of SAM in your body.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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