PHC2 Polyclonal Antibody


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Cat.No.:  EAb-0058
Product Name:  PHC2 Polyclonal Antibody
Product Overview:  Polyclonal Antibody to detect PHC2 in mouse samples.
Antibody Type:  Polyclonal
Immunogen:  Polyclonal antibody raised in rabbit against mouse PHC2 (polyhomeotic homolog 2) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.
Host:  Rabbit
Isotype:  IgG
Antibody Target:  PHC2
Purification:  Whole Anti-Sera
Appearance:  Colorless liquid
Formulation:  In PBS with 0.05% (W/V) sodium azide.
Applications:  ELISA.
Recommended Dilutions/Conditions:  ELISA: 1:500.
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  ELISA: Peptides.
Species Reactivity:  Mouse
Shipping:  Gel Pack
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q8IXK0
Alternative Name:  EDR2, HPH2, PH2
Scientific Background:  PHC2 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. The PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of lysine 119 on histone H2A, rendering chromatin heritably changed in its expressibility.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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