USP6NL Polyclonal Antibody


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Cat.No.:  EAb-0173
Product Name:  USP6NL Polyclonal Antibody
Product Overview:  Polyclonal antibody to detect endogenous levels of USP6NL in human, mouse and rat.
Antibody Type:  Polyclonal
Immunogen:  KLH-conjugated synthetic peptide encompassing a sequence within the center region of human USP6NL
Host:  Rabbit
Isotype:  IgG
Antibody Target:  USP6NL
Purification:  Affinity purified
Appearance:  Colorless liquid
Formulation:  In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
Applications:  WB, IH
Recommended Dilutions/Conditions:  WB; 1:500 – 1:2000, IHC; 1:50 – 1:200
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  WB: Jurkat, RAW264.7, PC12 lysates; IHC: human breast cancer tissue
Species Reactivity:  Human, Mouse, Rat
Shipping:  Gel Pack
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q92738
Alternative Name:  KIAA0019, USP6 N-terminal-like protein, Related to the N-terminus of tre, RN-tre
Scientific Background:  USP6 N-terminal-like protein acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. It is also involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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