PAR6A Polyclonal Antibody


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Cat.No.:  EAb-0182
Product Name:  PAR6A Polyclonal Antibody
Product Overview:  Polyclonal antibody to detect endogenous levels of PAR6A in human samples
Antibody Type:  Polyclonal
Immunogen:  KLH-conjugated synthetic peptide of human PAR6A
Host:  Rabbit
Isotype:  IgG
Antibody Target:  PARD6A
Purification:  Affinity purified
Appearance:  Colorless liquid
Formulation:  In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
Applications:  WB, IHC
Recommended Dilutions/Conditions:  WB; 1:500 – 1:2000, IH; 1:50 – 1:100
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  WB: HT29; Jrukat; Raji; mouse testis; whole cell lysates; IHC: Rat kidney tissue
Species Reactivity:  Human
Shipping:  Gel Pack
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q9NPB6
Alternative Name:  PAR6A; Partitioning defective 6 homolog alpha; PAR-6; PAR-6 alpha; PAR-6A; PAR6C; Tax interaction protein 40; TIP-40
Scientific Background:  Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Regulates centrosome organization and function. Essential for the centrosomal recruitment of key proteins that control centrosomal microtubule organization.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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