SUV39H1 Monoclonal Antibody (42AT239.96.72)


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Cat.No.:  EAb-0242
Product Name:  SUV39H1 Monoclonal Antibody (42AT239.96.72)
Antibody Type:  Monoclonal
Immunogen:  Recombinant human SUV39H1 (N-terminal fragment).
Host:  Mouse
Isotype:  IgG1
Purification:  Protein G affinity purified.
Appearance:  Liquid
Formulation:  In PBS containing 0.09% sodium azide.
Applications:  ELISA, WB
Recommended Dilutions/Conditions:  ELISA (1:1,000)Western Blot (1:100-1:500).
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse
Shipping:  Blue Ice
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  O43463
Scientific Background:  SUV39H1 is one of the founding members of the SET domain protein family whose major function is the modulation of gene activity. SUV39H1 has been shown to possess intrinsic histone methyltransferase activity, and specifically methylates Lys9 of histone H3. The degree of methylation by SUV39H1 varies within distinct regions of the chromatin, as H3 Lys9 in constitutive pericentric heterochromatin is trimethylated, while in euchromatin it is dimethylated.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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