| Cat.No.: | EAb-0288 |
| Product Name: | SUMO Monoclonal Antibody |
| Antibody Type: | Monoclonal |
| Clone Designation: | 3B5 |
| Immunogen: | recombinant yeast Smt3 amino acids 1-97 |
| Host: | mouse |
| Isotype: | IgG1 |
| Appearance: | Liquid |
| Formulation: | 500 µg of protein G-purified antibody |
| Applications: | ELISA and WB |
| Shipping: | Room temperature |
| Storage: | -20°C |
| Storage Buffer: | TBS, pH 7.4, when reconsituted in 500 µl double distilled water |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q12306 |
| Alternative Name: | Small Ubiquitin-like Modifier;Smt3 |
| Scientific Background: | The small ubiquitin like modifier (SUMO) protein is similar in structure and function to ubiquitin. However, SUMO does not typically target proteins for degradation as does ubiquitin. SUMO is involved with the modification of a very diverse array of targets. Proteins involved with transcriptional regulation, DNA damage repair, genomic stability, nuclear transport, and histone modification are all subject to modification by SUMO. SUMO typically functions by covalently binding to a target protein, followed by regulation of protein:protein and protein:DNA interactions. The SUMO family of proteins is highly conserved from yeast to human. Invertebrates contain a single SUMO gene (Smt3 in yeast and smo-1 in C. elegans), with three members of SUMO being identified in vertebrates to date (SUMO-1, SUMO-2 and SUMO-3). |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0020 | Suz12 Polyclonal Antibody | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0100 | Chaetocin | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0103 | Recombinant Human SUZ12 293 Cell Lysate | Inquiry |
| EL-0132 | Recombinant Human SUV39H1 293 Cell Lysate | Inquiry |
| EL-0137 | Recombinant Human SUV420H1 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| SUDS3 | SUMO | SUMO1 | SUMO2 |
| SUMO3 | SUN1 | Surf6 | suv39h1 |
| SUV39H2 | SUV3L1 | SUV420H1 | SUV420H2 |
| SUZ12 | |||
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