DDX43 Polyclonal Antibody


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Cat.No.:  EAb-0306
Product Name:  DDX43 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  Recombinant protein of human DDX43
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB, IHC, ELISA
Recommended Dilutions/Conditions:  WB: 1:200-1:1000; IHC: 1:50-1:200
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human
Storage:  -20°C
Storage Buffer:  PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q9NXZ2
Alternative Name:  Cancer/testis antigen 13,CT13,DDX43,DDX43,DEAD box protein 43,DEAD box protein HAGE,HAGE,Helical antigen,Probable ATP dependent RNA helicase DDX43,Probable ATP-dependent RNA helicase DDX43
Scientific Background:  DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX43 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 43), also known as CT13 or HAGE, is a 648 amino acid protein that contains one KH domain, one helicase C-terminal domain and one helicase ATP-binding domain and belongs to the DEAD-box family. Expressed in testis and present at abnormally high levels in a variety of tumors, DDX43 is thought to function as an ATP-dependent RNA helicase that may play a role tumor transformation and metastasis.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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