ELAVL3 Polyclonal Antibody


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Cat.No.:  EAb-0314
Product Name:  ELAVL3 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide of human ELAVL3
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB, ELISA
Recommended Dilutions/Conditions:  WB: 1:200-1:1000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse
Storage:  -20°C
Storage Buffer:  PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q14576
Alternative Name:  ELAV (embryonic lethal abnormal vision Drosophila) like 3 (Hu antigen C),ELAV like protein 3,ELAV-like protein 3,ELAV3,Elavl3,Embryonic lethal,abnormal vision,drosophila,homolog-like,Hu antigen C,Hu-antigen C,HuC,HUCL,MGC20653,Paraneoplastic cerebellar degeneration associated antigen,Paraneoplastic cerebellar degeneration-associated antigen,Paraneoplastic limbic encephalitis antigen 21,PLE21
Scientific Background:  A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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