KDM4C Polyclonal Antibody


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Cat.No.:  EAb-0381
Product Name:  KDM4C Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide of human KDM4C
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB, ELISA
Recommended Dilutions/Conditions:  WB: 1:500-1:2000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse
Storage:  -20°C
Storage Buffer:  PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q9H3R0
Alternative Name:  bA146B14.1,GASC 1 protein,GASC-1 protein,GASC1,Gene amplified in squamous cell carcinoma 1 protein,JHDM3C,JmjC domain containing histone demethylation protein 3C,JmjC domain-containing histone demethylation protein 3C,JMJD2C,Jumonji domain containing 2C,Jumonji domain containing protein 2C,Jumonji domain-containing protein 2C,Kdm4c,KDM4C,Lysine (K) specific demethylase 4C,Lysine demethylase 4C,Lysine-specific demethylase 4C,TDRD14C,Tudor domain containing 14C
Scientific Background:  This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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