| Cat.No.: | EAb-0387 |
| Product Name: | SF3B3 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant Human Splicing factor 3B subunit 3 protien |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | IHC |
| Recommended Dilutions/Conditions: |
IHC 1:100-1:400 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Storage Buffer: | PBS with 0.05% Proclin300, 50% glycerol, pH7.4. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q15393 |
| Alternative Name: | KIAA0017,Pre mRNA splicing factor SF3b 130 kDa subunit,Pre-mRNA-splicing factor SF3b 130 kDa subunit,RSE1,SAP 130,SAP130,SF3b130,SF3B3,SF3B3_HUMAN,Spliceosome associated protein 130,Spliceosome-associated protein 130,Splicing factor 3b subunit 3 130kD,Splicing factor 3B subunit 3,STAF130 |
| Scientific Background: | This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0387 | SF3B3 Polyclonal Antibody | Inquiry |
| EAb-0804 | SF3B3 Polyclonal Antibody | Inquiry |
| EAb-2056 | SFMBT1 Polyclonal Antibody | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-3207 | SFMBT1 (His) | Inquiry |
| PE-3208 | SFMBT1 (GST) | Inquiry |
| Related Gene / Proteins | |||
| SF3B3 | SFMBT1 | SFMBT2 | |
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