Cat.No.: | EAb-0884 |
Product Name: | KDM8 Polyclonal Antibody |
Antibody Type: | Polyclonal |
Conjugate: | Unconjugated |
Host: | Rabbit |
Isotype: | IgG |
Purification: | Protein G Purified |
Appearance: | Liquid |
Formulation: | 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, PH 7.4. |
Applications: | ELISA, IHC |
Recommended Dilutions/Conditions: |
ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Species Reactivity: | Human |
Storage: | -20°C |
Warning: | For Research Use Only! Not For Use in Humans. |
Alternative Name: | Lysine-specific demethylase 8 (EC:1.14.11.27), KDM8, JMJD5, JmjC domain-containing protein 5, Jumonji domain-containing protein 5 |
Scientific Background: | Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation. |
Product Types | ||
◆ Cell Lines | ||
CL-0015 | Human KDM5B Knockout Cell Line 14bp deletion | Inquiry |
CL-0087 | Human KDM1A Knockout Cell Line 10bp deletion | Inquiry |
CL-0088 | Human KDM1B Knockout Cell Line 13bp deletion | Inquiry |
CL-0089 | Human KDM2B Knockout Cell Line 14bp deletion | Inquiry |
◆ Antibodies | ||
EAb-0071 | KDM1B Polyclonal Antibody | Inquiry |
Related Gene / Proteins | |||
KDM1 | KDM1A | KDM1B | KDM2 |
KDM2A | KDM2B | KDM3A | KDM3B |
KDM4 | KDM4A | KDM4B | KDM4C |
KDM4D | KDM4E | KDM5 | KDM5A |
KDM5B | KDM5C | KDM5D | KDM6A More > |
KDM6B | KDM6C | KDM7 | KDM7A |
KDM7B | KDM8 |
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