SUV39H2 Polyclonal Antibody

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Cat.No.:  EAb-0920
Product Name:  SUV39H2 Polyclonal Antibody
Antibody Type:  Polyclonal
Conjugate:  Unconjugated
Host:  Rabbit
Isotype:  IgG
Purification:  Affinity Purified
Appearance:  Liquid
Applications:  ChIP, IP, WB
Recommended Dilutions/Conditions:  WB, IP, ChIP; Recommended dilution: WB 1:500 - 1:2000, IP 1:50 - 1:200, ChIP 1:20 - 1:100
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  FLJ23414 antibody, H3 K9 HMTase 2 antibody, Histone H3 K9 methyltransferase 2 antibody, Histone lysine N methyltransferase H3 lysine 9 specific 2 antibody, Histone lysine N methyltransferase SUV39H2 antibody, KMT1B antibody, Lysine N methyltransferase 1B antibody, Suppressor of variegation 3 9 homolog 2 (Drosophila) antibody, Su(var)3 9 Drosophila homolog of 2 antibody, Suppressor of variegation 3 9 homolog 2 antibody, Suv39h2 antibody, SUV92_HUMAN antibody
Scientific Background:  SUV39H2 encodes a H3 HMTase that shares 59% identity with SUV39H1, but which differs by the presence of a highly basic N terminus. SUV39H2 is also responsible for creating HP1 binding sites in heterochromatin by methylation of histone H3-Lys9. Moreover, SUV39H2 specifically accumulates with chromatin of the sex chromosomes (XYbody), which undergo transcriptional silencing during the first meiotic prophas.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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