KDM8 Polyclonal Antibody, FITC Conjugated


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Cat.No.:  EAb-0964
Product Name:  KDM8 Polyclonal Antibody, FITC Conjugated
Antibody Type:  Polyclonal
Conjugate:  FITC
Host:  Rabbit
Isotype:  IgG
Purification:  Protein G Purified
Appearance:  Liquid
Formulation:  0.03% Proclin 300. 50% Glycerol, 0.01M PBS, PH 7.4.
Applications:  ELISA
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  Lysine-specific demethylase 8 (EC:1.14.11.27), KDM8, JMJD5, JmjC domain-containing protein 5, Jumonji domain-containing protein 5
Scientific Background:  Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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