MINA Polyclonal Antibody, Biotin Conjugated


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Cat.No.:  EAb-0965
Product Name:  MINA Polyclonal Antibody, Biotin Conjugated
Antibody Type:  Polyclonal
Conjugate:  Biotin
Host:  Rabbit
Isotype:  IgG
Purification:  Protein G Purified
Appearance:  Liquid
Formulation:  0.03% Proclin 300. 50% Glycerol, 0.01M PBS, PH 7.4.
Applications:  ELISA
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA, 60S ribosomal protein L27a histidine hydroxylase, Histone lysine demethylase MINA, MYC-induced nuclear antigen, Mineral dust-induced gene protein, Nucleolar protein 52, Ribosomal oxygenase MINA, ROX, MINA
Scientific Background:  Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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