| Cat.No.: | EAb-1116 |
| Product Name: | EYA2 Polyclonal Antibody, Biotin Conjugated |
| Antibody Type: | Polyclonal |
| Conjugate: | Biotin |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Protein G Purified |
| Appearance: | Liquid |
| Formulation: | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4. |
| Applications: | ELISA |
| Species Reactivity: | Human |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Alternative Name: | EYA2, EAB1 |
| Scientific Background: | Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1. |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-1115 | EYA2 Polyclonal Antibody, FITC Conjugated | Inquiry |
| EAb-1116 | EYA2 Polyclonal Antibody, Biotin Conjugated | Inquiry |
| EAb-1120 | EYA2 Polyclonal Antibody | Inquiry |
| EAb-1127 | EYA2 Polyclonal Antibody, HRP Conjugated | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-2341 | Recombinant Human EYA1 protein | Inquiry |
| Related Gene / Proteins | |||
| EYA1 | EYA2 | EYA3 | |
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