USP5 Polyclonal Antibody

Product Datasheets
  • Specification
  • Target Information
  • Related Products
Cat.No.:  EAb-1487
Product Name:  USP5 Polyclonal Antibody
Antibody Type:  Polyclonal
Conjugate:  Unconjugated
Host:  Rabbit
Isotype:  IgG
Purification:  Protein G Purified
Appearance:  Liquid
Formulation:  0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
Applications:  ELISA, IHC, WB
Recommended Dilutions/Conditions:  ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human, Mouse
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  Ubiquitin carboxyl-terminal hydrolase 5, Deubiquitinating enzyme 5, Isopeptidase T, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5, USP5, ISOT
Scientific Background:  Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

Online Inquiry

For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Products
Featured Products / Services

Histone Post-translational Modification Analysis

RNA Methylation Analysis

USA

Enter your email here to subscribe.

Follow us on

Easy access to products and services you need from our library via powerful searching tools

Copyright © Creative BioMart. All Rights Reserved.