MINA Polyclonal Antibody


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Cat.No.:  EAb-1920
Product Name:  MINA Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  This antibody was raised against a peptide within the C-terminal region of human MINA.
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  55 kDa
Purification:  Affinity Purified
Appearance:  Liquid
Formulation:  Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.
Applications:  WB: 1:500 - 1:2,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  MINA (MYC Induced Nuclear Antigen) is an oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated Lys-9 on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on His-39. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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