JMJD2B / KDM4B Polyclonal Antibody


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Cat.No.:  EAb-1944
Product Name:  JMJD2B / KDM4B Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  This JMJD2B / KDM4B antibody was raised against a peptide within the C-terminal region of human JMJD2B.
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  142 kDa
Purification:  Affinity Purified
Appearance:  Liquid
Formulation:  Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.
Applications:  ICC/IF: 1:2,000 dilution; IP: 10 µl per IP; WB: 1:500 - 1:1,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Species Reactivity:  Human
Storage:  -20°C
Warning:  For Research Use Only! Not For Use in Humans.
Scientific Background:  JMJD2B / KDM4B (JmjC domain-containing histone demethylation protein 3B, Jumonji domain-containing protein 2B, JHDM3B) is a histone demethylase that has been shown to demethylate histone H3 trimethylated at lysine 9. JMJD2B / KDM4B is physically associated with the MLL2 methyltransferase complex where it serves as a co-factor for ERα-mediated transcriptional activation.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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