| Cat.No.: | EAb-2063 |
| Product Name: | Rsf1 Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | This Rsf1 antibody was raised against a His-Tagged fusion protein corresponding to amino acids 165-350 of Drosophila Rsf1. |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 58 kDa |
| Purification: | Affinity Purified |
| Appearance: | Liquid |
| Formulation: | PBS containing 0.1% sodium azide, 0.2 mg/ml BSA and 35% glycerol. |
| Applications: | WB: 1:1,000 - 1:5,000 dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Drosophila |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | Rsf-1 (Remodeling and spacing factor 1) is a member of RSF complex. This complex consists of two subunits: Rsf-1 and SNF2H. RSF possesses a chromatin remodeling activity and a chromatin assembly activity. Rsf-1 assembles the nucleosomes randomly with its histone chaperone activity. The resulting nucleosomes are then redistributed by the ATP-utilizing nucleosome mobilization factor SNF2H into a periodic array. Rsf-1 can be involved in transcriptional repression when it is recruited to DNA via the DNA binding of Gal4 or in transcriptional coactivation when associated with hepatitis B virus pX protein (HBX). In response to hepatitis B infection, Rsf-1 can bind to the viral transcription activator pX, which then coactivates the transcription factor NFκB, thus supporting the life cycle of the viral genome. Additionally, Rsf-1 is thought to be a potent oncogene, with elevated expression observed in ovarian carcinomas. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0197 | Human RSPH3 Knockout Cell Line | Inquiry |
| ◆ Antibodies | ||
| EAb-2063 | Rsf1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| Rsf1 | RSPH3 | ||
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