| Cat.No.: | EAb-2115 |
| Product Name: | Dicer Monoclonal Antibody |
| Antibody Type: | Monoclonal |
| Immunogen: | This Dicer antibody was raised against a recombinant protein corresponding to amino acids 1638-1899 of mouse Dicer. |
| Host: | Mouse |
| Isotype: | IgG1 |
| Molecular Weight: | 245 kDa |
| Purification: | Protein G Chromatography |
| Appearance: | Liquid |
| Formulation: | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. |
| Applications: | WB: 1 - 2 µg/ml dilution^Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Species Reactivity: | Human, Mouse |
| Storage: | -20°C |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Scientific Background: | Dicer is a double-stranded RNase and part of the micro-RNA (miRNA) loading complex (miRLC), which is composed of Dicer, Ago2 and TARBP2. Dicer is required for formation of the RNA induced silencing complex (RISC). Dicer and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto Ago2. Dicer also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the destruction of complementary RNAs. |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0174 | Human DISP1 Knockout Cell Line | Inquiry |
| ◆ Antibodies | ||
| EAb-0214 | Dimethyl-lysine Polyclonal Antibody | Inquiry |
| EAb-0215 | Dimethyl-lysine Polyclonal Antibody | Inquiry |
| EAb-2115 | Dicer Monoclonal Antibody | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-2531 | Recombinant Human DIS3L protein | Inquiry |
| Related Gene / Proteins | |||
| Dicer | Dimethyl-Histone | DIS3L | DISP1 |
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