KDM6A/UTX Polyclonal Antibody


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Cat.No.:  EAb-2500
Product Name:  KDM6A/UTX Polyclonal Antibody
Product Overview:  Rabbit polyclonal to detect KDM6A/UTX
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide conjugated to KLH derived from within residues 400 - 500 of Human UTX.
Host:  Rabbit
Isotype:  IgG
Purification:  Immunogen affinity purified
Appearance:  Liquid
Formulation:  0.02% Sodium Azide
Applications:  WB, ICC/IF, ChIP
Species Reactivity:  Mouse, Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX) antibody/bA386N14.2 antibody/bA386N14.2 ubiquitously transcribed X chromosome tetratricopeptide repeat protein UTX antibody
Scientific Background:  Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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