| Cat.No.: | EAb-2515 |
| Product Name: | Aurora B Polyclonal Antibody |
| Product Overview: | Rabbit polyclonal to detect Aurora B |
| Antibody Type: | Polyclonal |
| Immunogen: | Synthetic peptide within Human Aurora B aa 1-100 conjugated to keyhole limpet haemocyanin. |
| Host: | Rabbit |
| Isotype: | IgG |
| Purification: | Immunogen affinity purified |
| Appearance: | Liquid |
| Formulation: | 0.02% Sodium Azide |
| Applications: | ICC/IF, IHC-Fr, IHC-P, IP, WB |
| Species Reactivity: | Mouse, Rat, Hamster, Human, Pig |
| Storage: | -20°C. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Q96GD4 |
| Alternative Name: | AURKB; AIK2; AIM-1; AIM1; ARK2; AurB; IPL1; PPP1R48; STK12; STK5; aurkb-sv1; aurkb-sv2; aurora kinase B |
| Scientific Background: | May be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Phosphorylates 'Ser-10' and 'Ser-28' of histone H3 during mitosis. Required for kinetochore localization of BUB1 and SGOL1. Interacts with INCENP. |
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
