PADI4/PAD4 Polyclonal Antibody


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Cat.No.:  EAb-2539
Product Name:  PADI4/PAD4 Polyclonal Antibody
Product Overview:  Rabbit polyclonal to detect PADI4/PAD4
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide corresponding to Human PADI4/ PAD4 (N terminal).
Host:  Rabbit
Isotype:  IgG
Purification:  Protein A purified
Appearance:  Liquid
Formulation:  1.21% Tris, 2% Sucrose, 0.75% Glycine
Applications:  WB, IP, ELISA, ICC/IF
Species Reactivity:  Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Q9UM07
Alternative Name:  EC 3.5.3.15 antibody/HL 60 PAD antibody/HL-60 PAD antibody
Scientific Background:  Catalyzes the citrullination/deimination of arginine residues of proteins. Citrullinates histone H3 at 'Arg-8' and/or 'Arg-17' and histone H4 at 'Arg-3', which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCOA2/GRIP1.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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