PADI4/PAD4 Polyclonal Antibody


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Cat.No.:  EAb-2551
Product Name:  PADI4/PAD4 Polyclonal Antibody
Product Overview:  Rabbit polyclonal to detect PADI4/PAD4
Antibody Type:  Polyclonal
Immunogen:  Synthetic peptide corresponding to amino acids 1-15 of human PADI4, conjugated to KLH via a C-terminal added cysteine residue
Host:  Rabbit
Isotype:  IgG
Purification:  Ion Exchange Chromatography
Appearance:  Liquid
Formulation:  pH: 7.40; 0.097% Sodium azide, 0.0268% PBS
Applications:  IP, WB
Species Reactivity:  Human
Storage:  -20°C.
Warning:  For Research Use Only! Not For Use in Humans.
Alternative Name:  EC 3.5.3.15 antibody/HL 60 PAD antibody/HL-60 PAD antibody
Scientific Background:  Catalyzes the citrullination/deimination of arginine residues of proteins. Citrullinates histone H3 at 'Arg-8' and/or 'Arg-17' and histone H4 at 'Arg-3', which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCOA2/GRIP1.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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